Pulsed diode laser-based monitor for singlet molecular oxygen
نویسندگان
چکیده
منابع مشابه
Pulsed diode laser-based monitor for singlet molecular oxygen.
Photodynamic therapy (PDT) is a promising cancer treatment. PDT uses the affinity of photosensitizers to be selectively retained in malignant tumors. When tumors, pretreated with the photosensitizer, are irradiated with visible light, a photochemical reaction occurs and tumor cells are destroyed. Oxygen molecules in the metastable singlet delta state O2(1Delta) are believed to be the species th...
متن کاملPulsed diode laser-based singlet oxygen monitor for photodynamic therapy: in vivo studies of tumor-laden rats.
Photodynamic therapy (PDT) is a promising cancer treatment that involves optical excitation of photosensitizers that promote oxygen molecules to the metastable O(2)(a(1)Delta) state (singlet oxygen). This species is believed to be responsible for the destruction of cancerous cells during PDT. We describe a fiber optic-coupled, pulsed diode laser-based diagnostic for singlet oxygen. We use both ...
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Photodynamic therapy (PDT) is a promising cancer treatment. PDT uses photosensitizers that are selectively retained in malignant tumors. When tumors, pretreated with the photosensitizer, are irradiated with visible light, a photochemical reaction occurs and tumor cells are destroyed. Oxygen molecules in their metastable singlet delta state, O2(∆), are believed to be the species that destroys ca...
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Enzyme-based electrochemical biosensors are an inspiration for the development of (bio)analytical techniques. However, the instability and reproducibility of the reactivity of enzymes, combined with the need for chemical reagents for sensing remain challenges for the construction of useful devices. Here we present a sensing strategy inspired by the advantages of enzymes and photoelectrochemical...
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BACKGROUND There has been growing patient demand for laser technology to treat rhytids and to refine skin texture without the associated lifestyle hindrance common to ablative cutaneous procedures. Nonablative laser systems have been developed to meet this need and, in many instances, have replaced ablative lasers as the preferred treatment modality. OBJECTIVE To review long-pulsed diode lase...
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ژورنال
عنوان ژورنال: Journal of Biomedical Optics
سال: 2008
ISSN: 1083-3668
DOI: 10.1117/1.2927465